Pharmacokinetics Researcher (Pharmaceutical Analysis)

 You will be engaged in the research and development of small molecule pharmacokinetics, mainly responsible for the in vivo and in vitro ADME screening of drug candidates. You will have access to various advanced laboratory instruments, master the most cutting-edge instrumental analysis methods and different experimental design schemes, participate in the screening process of new drugs pre-clinical in vitro pharmacokinetics, and select promising drugs to clinical phase. You will have the opportunity to participate domestic and international pharmaceutical conferences and communicate with experts in the industry. 

Job responsibilities

In vitro pharmacokinetics direction:

1. Use in vitro models or related biological substrates (plasma, cells, microsomes, buffer, etc.) to conduct in vitro screening tests of drug candidates, including physical and chemical properties, drug distribution, drug metabolism and drug-drug interaction;

2, Perform sample analysis using high performance liquid phase and triple quadrupole mass spectrometry tandem technology and high-resolution mass spectrometer;

3. Design and carry out in vitro drug metabolism experiments, collect and sort out experimental data, and prepare experimental protocols and reports.

in vivo Pharmacokinetic:

1. Using LC-MS to analyze drugs and metabolites in biological samples (animal blood, tissues, etc.) and conduct PK/PD correlation research;

2, the use of analytical instruments (HPLC, LC/MS/MS) to examine the reaction of the efficacy in the body, the detection of the drug concentration;

3. Design and carry out in vivo drug metabolism experiments, collect and sort out experimental data, and prepare experimental protocols and reports.

Job requirements

1, Pharmacy, pharmacology, pharmaceutical analysis, drug metabolism, pharmaceutical chemistry, natural pharmaceutical chemistry, biology or other related major or research direction, doctoral degree;

2. Familiar with the process of new drug research and development, solid professional knowledge and theoretical foundation, proficient in liquid chromatography-mass spectrometry and other related technologies, familiar with the design and operation of preclinical pharmacokinetic experimental schemes, pharmacokinetic software and calculation methods;

3, love the pharmaceutical research and development industry, with fast learning ability and adaptability, good analytical skills, communication and coordination skills and team spirit, leadership, a strong sense of responsibility.

4, with good scientific research ability, able to independently undertake projects, develop project plans, and lead the team to solve problems in the project;

5, Englishv and Chinese proficiency, good English communication, reading English literature and writing English experimental plan ability.

Require Chinese and English resume