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Scientist (Contract)

Genentech
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Scientist (Contract), in vitro biochemical and cellular assay development, Small Molecule Biochemical and Cellular Pharmacology

 

Description:

  • 6-month (at least) contractor position
  • The Biochemical and Cellular Pharmacology Department develops and implements quantitative biochemical and cellular assays to determine the potency and mechanisms of drug molecules.
  • The Scientist will apply cutting-edge assay technologies and automation to develop robust biochemical and cellular assays suitable for screening our novel molecules against emerging targets in immunology and cancer immunology.
  • The Scientist will support hit compound potency measurements and characterization as needed.

 

Requirements:

  • Analytical and quantitative mindset
  • Organized and detail-oriented
  • Highly collaborative and willing to learn
  • Analyze and present data (written/oral) and troubleshoot as needed
  • Document work in an electronic laboratory notebook (ELN)
  • Prepare written standard operating protocols (SOP) and assist in transferring assays to other scientists as needed

 

Qualifications:

  • Bachelor’s or Master’s degree in Biochemistry, Biology or an equivalent quantitative science field
  • At least 2 years of experience developing, running and troubleshooting quantitative 384-well plate based biochemical and cellular assays in a drug discovery setting
  • Strong working knowledge of absorbance, fluorescence, TR-FRET and fluorescence polarization assays
  • Experience using plate readers such as EnVision, SpectraMax, PHERAstar, TECAN M1000 and MSD Sector
  • Ability to use laboratory automation such as Echo, Biomek i5/i7/FXP, HP D300e Multidrop Combi