Postdoctoral Research Fellow

A postdoctoral research position is available in the lab of Dr. Hrish Kulkarni, a NIH-funded laboratory in the UCLA Division of Pulmonary and Critical Care. We are seeking a postdoctoral fellow to investigate how C3, a key protein in the immune system, affects the severity of acute lung injury and ARDS. The overarching goal of our research program is to determine how epithelial cell-derived proteins can be harnessed to mitigate the risk of acute lung injury in various settings, to ultimately reduce the burden of end-stage lung disease. We utilize state-of-the-art technical modalities including conditional knockout mouse models, primary epithelial cell lines, flow cytometry, ELISA, protein and DNA-based molecular biology, biochemistry, cell/tissue culture, fluorescence and confocal microscopy, and DNA/RNA sequencing. The project also involves analyzing single cell RNA-sequencing and spatial transcriptomic datasets. 

Eligible candidates must have a Ph.D. in biomedical sciences. The project involves both in vitro and in vivo experimentation at the intersection of immunology, cell biology, and bioinformatics. Experience with standard cellular biology techniques and working with murine in vivo models is required, as well as microscopy and flow cytometry. Experience in bioinformatics is encouraged but is not mandatory.