Scientist / Senior Scientist - Flow Cytometry
Scientist / Senior Scientist - Flow Cytometry (Boston, MA) - 227084
Thermo Fisher's clinical research business is a leading global contract research organization and world leader in serving science. We are passionate, deliberate, and driven by our mission – to enable our customers to make the world healthier, safer, and cleaner.
Within our Analytical Services team, we have a functional service provider solution, which is a unique partnership that allows our customers to leverage the experience of our staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits.
In this role you will join the Cell and Gene Therapy Group to support the Analytical Development Team.
Essential Functions:
- Coordinate sample characterization (sample tracking, inventory, and testing) and data management/data integrity initiatives
- Develop and execute routinely automated test methods in support of Cell Therapy Process Development and some gene therapy activities (e.g., Flow Cytometry, Cell Culture, Cell differentiation assay, Cell based Potency Assay, Immuno-based assays, and viral genome titer ddPCR etc.).
- Involve in troubleshoot, optimize, and trend assay performance
- Involve in writing the technical report, project progress reports, analytical development protocols and reports.
- Involve in method transfer assays to QC if needed.
- Maintain excellent written documentation (e.g. lab notebook and test forms)
- Assist with lab organization and compliance with lab safety protocols
- This position is lab-based and requires 80% lab work and 20% sample/data management.
- Generate all training procedures for users to ensure smooth operation of the test method.
- Be a strong team player contributing to group priorities and deliverables.
At PPD, part of Thermo Fisher Scientific we hire the best, develop ourselves and each other, and recognize the power of being one team. We offer continued career advancement opportunities, award winning training and benefits focused on the health and wellbeing of our employees.
To learn how PPD, part of Thermo Fisher Scientific can advance your career, apply now!
Education and Experience:
- Bachelor's degree or equivalent and relevant formal academic / vocational qualification
- Previous industry experience that provides the knowledge, skills, and abilities to perform the job:
- Scientist: With a bachelor’s degree comparable to 2+ years, with a master’s degree comparable to 0-2+ years.
- Senior Scientist: With a bachelor’s degree comparable to 4+ years, with a master’s degree comparable to 2+ years, with a PhD comparable to 0-2+ years.
In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.
Preferred Experience:
- At least 1 year of relevant industry experience in the cell and/or gene therapy space
- Relevant industrial laboratory experience in assay/analytical development of cell and/or gene therapies
- Familiarity with cell therapy techniques like Flow cytometry and FACS data analysis.
- Experience with stem cells.
- Experience with assay development for assessment of cell therapy-based products including identity, purity, and potency
- Familiarity with automated assay development and robotic liquid handler (Hamilton and TECAN) operations.
Knowledge, Skills and Abilities:
- Experience with sample management and ELN/LIMS systems strong preferred
- Hands-on experience with the following techniques: Flow Cytometry, Cell culture, Cell based Potency Assay, ELISA, and ddPCR.
- Understanding with regulatory authority, compendia and ICH guidelines
- Ability to understand and independently apply GMPs and /or GLPs to everyday work about documentation and instrument use
- Ability to utilize Microsoft Excel and Word to perform tasks
- Ability to independently optimize analytical methods
- Excellent written and oral communication skills
- Time management and project management skills
- Problem solving and troubleshooting abilities
- Ability to work in a collaborative work environment with a team
Working Environment:
PPD, part of Thermo Fisher Scientific values the health and well being of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive. Below is listed the working environment/requirements for this role:
- Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.
- Able to work upright and stationary and/or standing for typical working hours.
- Able to lift and move objects up to 25 pounds.
- Able to work in non-traditional work environments.
- Able to use and learn standard office equipment and technology with proficiency.
- May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.
- Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.
- As a condition of employment with PPD, in this role, you must have received your Covid-19 vaccine and you must disclose proof of your vaccination status upon employment.
Our 4i Values:
Integrity – Innovation – Intensity – Involvement
If you resonate with our 4i values above, and ultimately wish to accelerate the delivery of safe and effective therapeutics for some of the world’s most urgent health needs, submit your application – we’d love to hear from you!