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INTERNSHIP - Application Science, Small-Molecule Library Enumeration

OpenEye, Cadence Molecular SciencesĀ an industry leader in computational molecular design, uses a scientific approach to deliver rapid, robust, and scalable software, toolkits, and technology & design services for the advancement of pharmaceuticals, biologics, agrochemicals, and flavors and fragrances. We are passionate about science and about taking care of our team members, with leaders supporting your development and recognizing your contributions by providing an unmatched total compensation package in a collaborative, caring, energetic and fun work environment.

OpenEye is looking to fill an intern position to work on a tool for the enumeration of libraries of synthetically accessible molecular structures. This tool serves as an idea generator for drug discovery projects. Using our cloud platform, ORION, the intern will work to validate the tool by curating sets of chemical reactions from available databases to ensure that our hand-coded rules for chemical transformations are both realistic and appropriately broad. Experience in a synthetic organic chemistry lab is required, as is a strong interest in learning about how molecules are represented and handled in molecular modeling projects. No coding experience is required for this position.

Why intern at OpenEye, Cadence Molecular Science?
Gain industry experience in a professional, leading-edge scientific software engineering environment. Develop your problem solving abilities while contributing to challenging scientific and engineering projects. OECMS provides a fantastic opportunity to network with world-class scientists and engineers and determine the next steps in your career.

Key Learnings:
  • Experience with state-of-the-art computational chemistry packages
  • Access to professional developers and customer-facing scientists, knowledge about the interface between reaction chemistry and cheminformatics,
  • Gain experience working at the interface of a software company and the drug-discovery enterprise.

Education:
Minimally a currently enrolled 2nd year college student working on a degree in chemistry

What you should have:
  • Extensive coursework in, and understanding of, synthetic organic chemistry (at least two years)
  • Some practical synthetic chemistry or medicinal chemistry lab work in a research setting.
  • Understanding of and experience with searching common reaction databases.

The following are a PLUS, but not required:
  • Previous experience in a medicinal chemistry setting
  • Previous work with/understanding of cheminformatics
  • Experience coding in Python
OpenEye Scientific Software is an Equal Opportunity Employer.