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Ionis Pharmaceuticals, Inc., one of the 2020 Best Places to Work in San Diego, is in the North San Diego County city of Carlsbad. For more than 30 years, Ionis has been the leader in RNA-targeted therapy, pioneering new markets and changing standards of care with our novel antisense technology. Ionis currently has three marketed medicines – Spinraza, the standard of care for all forms of spinal muscular atrophy; Tegsedi, the first approved RNA-targeted therapy for polyneuropathy caused by hereditary ATTR (transthyretin) amyloidosis; and Waylivra, the only approved treatment for familial chylomicronemia syndrome (FCS). Ionis has a premier late-stage pipeline highlighted by our industry-leading neurological and cardiometabolic franchises. Scientific innovation began and continues at Ionis with the understanding that sick people depend on the success of the company. This belief drives Ionis’ vision of becoming one of the most successful biotechnology companies.

As the first company to fully harness the power of RNA technology for human therapeutics, Ionis’ platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. Ionis’ medicines span multiple therapeutic areas, routes of administration and diverse patient populations, and Ionis innovation is driving meaningful progress for many of the most challenging health issues.

Ionis is building upon our innovative research and drug development excellence to provide greater value to patients. Based on the breadth and remarkable progress of our pipeline, Ionis is projecting to have a vast number of new transformational products on the market in the coming years. Ionis is well positioned financially to deliver on our strategic goals.

Ionis is a challenging, motivating and rewarding environment designed to foster innovation and scientific excellence. Our success is a direct result of our outstanding employees. We are interested in bringing together individuals with different skill sets into this creative environment to be part of a productive team. Join us and experience our unique culture while you develop and expand your career.

We are seeking a highly motivated and outstanding individual to join our Core Research group as a Postdoctoral Fellow. The selected candidate will develop novel strategies to manipulate gene expression via antisense oligonucleotides. The successful candidate will be an innovative thinker with the ability to work independently to conceptualize, implement and meticulously carry out experiments. This position offers a unique opportunity to conduct experiments in a rich drug discovery environment and produce original research for publication.

  • A Ph.D. in gene expression regulation, particularly at the transcription level
  • Strong background in molecular and cellular biology
  • Solid track record of research productivity by multiple publications in quality peer-reviewed journals
  • Strong organizational, written, and verbal skills
  • Ability to work both independently and as part of a laboratory team
  • Ability to be productive and successful in an intense work environment
  • Please include a CV, cover letter, and list of three references in your application

Excellent salary and benefits package offered.
For more information about Ionis and to apply for this position, please visit o