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MURI Program: Image-Based Experimental Hemodynamics

DUE is home to IEL and the CRL which is administering the Multidisciplinary Undergraduate Research Institute (MURI) both in the academic year and the summer, which creates and supports multidisciplinary research teams consisting of undergraduate and graduate students, postdoctoral fellows, senior staff and faculty. The primary purpose of these teams is to provide undergraduates a unique opportunity to gain research skills by working with mentors on real world problems.

Overview of department:

The Department of Mechanical and Energy Engineering offers high quality education and research opportunities to help prepare students for the professional world. The mission of the department is to provide with the best educational and research curriculum possible, giving the tools and knowledge needed to succeed in the field of Mechanical and Energy Engineering. One of the fundamental – and most diverse – engineering disciplines, mechanical and energy engineering equips men and women to make a difference on the smallest micro-scale level, as well as in large, complex systems. Each day, mechanical engineering principles are used in the conception, design, development, and manufacture of almost every product or process known to man.

Project summary:

Working on the development of the flow and pressure measurement in 3-D printed human arteries. Validate the pressure measurement via comparisons with medical measured pressure waveforms.

Specific tasks that the MURI student will complete: 

  1. Image segmentation from CT and MRI imaging data
  2. Image process to make stenosis
  3. 3-D printing
  4. Measurement and validation of pressure and velocity waveforms in 3-D printed human arties
  5. Quantification of compliance and resistances

Specific qualifications (knowledge, skills, class standing, etc) we desire the MURI candidate to have:

Knowledge on physiology and pathology on human cardiovascular circulation and experiences on Electrical circuit, Labview, Matlab, Creo(3D CAD), NetFAB 3D printing are helpful to accomplish the project.

Learning objectives as outlined in the IUPUI Profiles of Undergraduate Learning:
By the end of this position assignment, the student will meet the following learning objectives

  1. Problem Solver: First-hand experiences on image segmentation from CT/MRI DICOM, 3-D printing, experimental measurement of blood pressure and velocity in silicon human arteries.
  2. Communicator: Co-authors of journal and/or conference papers.