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Research Associate II (Contractor)

Genentech
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The Advanced Cell Engineering (ACE) Hub in the Cell Therapy department at Genentech is seeking a talented and enthusiastic candidate for a full-time lab-based Research Associate II contractor position. The ACE Hub is an interdisciplinary team with a mission to accelerate drug discovery in gRED through the development, application, and enablement of genome engineering and synthetic biology technologies. 

 

The successful candidate will support the needs of the ACE Hub, particularly in the engineering and profiling of cells for cell therapy development and disease modeling used across Genentech. They will be expected to work independently and make technical contributions within a dynamic, fast-paced and highly collaborative research environment. This is a one-year position with the possibility of extension.


 

Responsibilities:

  • Generate engineered cells(including cancer cell lines, iPSCs, and primary cells) using stable integration (both lentivirus and piggybac) and CRISPR gene editing
  • Transfection/ gene editing optimization
  • Troubleshoot cell engineering protocols
  • Characterize engineered cells using genomics and molecular assays
  • Follow and establish SOPs, maintain and quality check cell lines in culture

 

Who You Are (Requirements):

  • A self-motivated candidate with MS + 3 years industry experience, or PhD in Molecular Biology, Cell Biology, Genetics, or a related discipline.
  • Qualified candidates must have demonstrable strong mammalian cell culture techniques and ability to generate high-quality data. Prior experience with iPSCs and primary T cells is highly desirable.
  • Candidates must have strong hands-on proficiency in molecular and cell biology methodologies including PCR, lentivirus/piggyBac, transfection, CRISPR engineering and flow cytometry (FACS). 
  • Skilled in processing and analyzing data from molecular and cellular assays using softwares (e.g., GraphPad Prism, FlowJo)
  • Excellent written and verbal communication skills, and able to generate high quality data  and present at team meetings.
  • Highly organized with a proven ability to multi-task and execute deliverables across a diverse array of projects. 
  • Strong troubleshooting capabilities with a proactive mindset and a strong eagerness to learn new technical skills.
  • Collaborative and team-oriented. 
  •  Ready to start ASAP