Chemistry Intern

AVIDITY BIOSCIENCES 

At Avidity Biosciences, we are passionate about the impact of every employee in realizing our vision of improving people’s lives by delivering a new class of RNA therapeutics. Avidity is revolutionizing the field of RNA with its proprietary AOCs, which are designed to combine the specificity of monoclonal antibodies with the precision of oligonucleotide therapies to address targets and diseases previously unreachable with existing RNA therapies. If you are a committed, solution-oriented thinker, join us in making a difference and become part of our growing culture that is integrated, collaborative, agile and focused on the needs of patients. 

Avidity Biosciences, Inc.'s mission is to profoundly improve people's lives by delivering a new class of RNA therapeutics - Antibody Oligonucleotide Conjugates (AOCs™). Utilizing its proprietary AOC platform, Avidity demonstrated the first-ever successful targeted delivery of RNA into muscle and is leading the field with clinical development programs for three rare muscle diseases: myotonic dystrophy type 1 (DM1), Duchenne muscular dystrophy (DMD) and facioscapulohumeral muscular dystrophy (FSHD). Avidity is broadening the reach of AOCs with its advancing and expanding pipeline, including programs in cardiology and immunology through internal discovery efforts and key partnerships. Avidity is headquartered in San Diego, CA. For more information about our AOC platform, clinical development pipeline, and people, please visit 

www.aviditybiosciences.com and engage with us on LinkedIn and X.  

CHEMISTRY INTERN 

Will work in the Chemistry Department of Avidity Biosciences on projects related to our early drug discovery. This is a hands-on position responsible for assisting with the design, synthesis, and analysis of drug like molecules, oligonucleotides, and antibody oligonucleotide conjugates. The ideal candidate will have a good understanding of the basics of general chemistry, organic chemistry, and biology. The candidate is expected to be a quick learner who enjoys drug discovery research. This individual will work under the supervision of a scientist. 

RESPONSIBILITIES

• Help to carry out synthesis and purification of oligonucleotides, peptides, small molecules on automated synthesizers and other platforms.  
• Help to conduct bioconjugations of oligonucleotides with various vehicles such as: proteins, peptides, and antibodies. 
• Develop and/or perform analytical methods to characterize molecules using instruments such as: HPLCs, MS, UV, SDS-PAGE. 
• Perform experiments to assess biophysical and biochemical profiles of bioconjugates. · Prepare buffers, reagents, and materials required to enable synthesis and analytical work. · Provide written and presentation updates to key stakeholders. 

DESIRED MAJORS/MINIMUM QUALIFICATIONS + SKILLS 

• Undergraduate college students, in chemistry, biotechnology, or related discipline.
• Must be attentive in carrying out responsibilities, detail oriented, and highly organized. · Must have good communication skills and be a trustworthy team player. · Knowledge of safe general laboratory techniques. 
• Relevant work experience in research labs is a plus. 
• Ability to multi-task well and work in a fast-paced environment.
• Willingness to learn and build upon a career in Research.
• Experience and proficiency with MS Office applications (Outlook, Word, Excel and Powerpoint)