Discovery Biology - Intern

Role Summary:

The role supports early-stage partnered and wholly owned drug discovery programs across Immunology, Oncology, and undisclosed by designing, executing, and analyzing robust cell-based assays. This position plays a key role in developing and optimizing in vitro cellular and primary cell–based protocols, generating quantitative data to assess drug potency, mechanism, and lead progression. Working independently and in close collaboration with cross-functional scientists, the role contributes to target identification, screening, and optimization efforts, ensures accurate and timely data capture in enterprise systems, and proactively introduces new techniques and efficiencies to accelerate discovery while upholding Nurix’s collaborative, hands-on, and results-driven culture.

Responsibilities 

• Plan, execute, and analyze in vitro cellular assays to support small molecule and biologic discovery efforts, mechanistic studies, and new target identification
• Perform protocols for primary cell isolation and antibody-based protein quantification methods 
• Proactively learn new techniques and propose new efficiencies to accelerate drug discovery (flow cytometry, ELISA, simple and traditional western blot, HTRF, fluorescent based reporter assays, assay development, ect.)
• Learn GraphPad Prism to analyze experimental data to quantify drug potency and activity
• Upload data into electronic lab notebooks and enterprise databases with high level of accuracy and timeliness 
• Work closely with scientists from cross-functional disciplines, present findings to project teams, and become familiar with a professional biotechnology and pharmaceutical environment
• Conduct screens to identify new leads and monitor progress on drug optimization

Fit with Nurix Culture and Values

• Strong team orientation; highly collaborative
• Solutions and results-oriented focus
• Hands-on approach; resourceful and open to diverse points of view