Pharmacometrics Intern

Contract - 3 Months

Fully Remote

PR: $35-40/hr

Shift: Monday through Friday, 8am-  4pm/9am – 5pm (Flexible)

Job Description

The Clinical Pharmacology and Pharmacometrics Intern (CPPI) will perform research two areas: 1) Develop a Physiologically based Pharmacokinetics (PBPK) model to predict clinical cardiac safety ; 2) Develop a prototype of open-source-compatible noncompartmental analysis (NCA) automation toolkit. The CPPI will work closely with experienced clinical pharmacologists and pharmacometricians during the conceptualization, design, implementation, and presentation stages. A poster presentation and/or a manuscript will also be prepared at the conclusion of the first project (i.e., PBPK model development). The core duties and responsibilities of the CPPI are delineated below.

Job Responsibilities

• The primary goal of the first project for the CPPI is to develop and validate a PBPK model to inform the potential cardiac exposure and safety 
• The primary goal of the second project for the CPPI is to develop and validate an automated NCA platform that would enhance efficiency and reliability in NCA analysis for clinical pharmacology studies.
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Education & Qualifications

Required: 

• PhD candidate in Pharmaceutical Sciences, Data Sciences, Pharmacokinetics, Computer Science, Biomedical Engineering or related field
• No industry experience required
• Strong verbal and written communication skills 
• Interest in applying computation tools to drug development problems

 Preferred: 

• Exposure to clinical pharmacology, pharmacometrics, translational/mechanistic modeling and simulation
• Understanding of drug development and pharmacology
• Knowledge of statistical analysis software (e.g., Python, R), PK/PD modeling and simulation software (e.g., PK Sim, Gastroplus, SimCYP)