Biochemistry-Cell Biology Senior Scientist

Biochemistry-Cell Biology Senior Scientist at Akttyva Therapeutics
 

Akttyva Therapeutics, a recently launched drug-discovery company, is at the forefront of accelerating drug development through innovation and technology. Founded by a distinguished group of pharmaceutical industry veterans, scientists, and entrepreneurs, our mission is to advance the drug discovery process. We have developed an AI-powered drug discovery platform that seamlessly integrates with experimental studies, enhancing our ability to design novel therapeutics efficiently and effectively. At Akttyva Therapeutics, we are committed to pushing the boundaries of science to create solutions that will lead to better health outcomes and affordable treatments worldwide. Join us in our journey to transform the future of medicine. 

Position Overview: As the Senior Scientist in Biochemistry-Cell Biology at Akttyva Therapeutics, you will develop/optimize cutting-edge in-vitro assays for screening among potential drug candidates, identified through the use of the AIDE360 drug discovery platform. 
 

Relationships: In this role, you will nurture a dynamic internal network, interacting with computational people and fostering collaborative ties with the entire scientific team. Externally, you will be a key figure in representing Akttyva in strategic partnerships across both commercial and academic spheres, ensuring a cohesive effort towards groundbreaking drug discovery endeavors. 
 

Key Responsibilities:  
 

· Design and conduct thermal shift assay or other format binding assays, immunoassays, western blotting and other relevant methods to screen experimentally among drug candidates. 

· Develop and optimize permeability assays using an endothelial monolayer transwell system and commercially available multicell systems, modeling the air-blood barrier in the lung, to characterize lead drug candidates.  

· Maintain and manipulate various cell types in support of drug screening activities and drug development. 

· Lead and mentor research associates in experimental design, data analysis, and troubleshooting. 

· Collaborate with computational chemist and other scientific teams to support the development of novel therapeutics. 

· Analyze and interpret experimental data, presenting findings in internal meetings and external conferences. 

· Stay current with the latest scientific literature and technological advancements in drug development and use of AI in drug discovery. 

· Contribute to the preparation of scientific manuscripts, patent applications, and grant proposals. 

· Ensure compliance with all laboratory safety protocols and maintain accurate records of all research activities. 

Qualifications:
 

Educational Background: A Ph.D. in Biochemistry, Molecular Biology, Cell Biology or other related field with about 3+ years of relevant experience is required.  
 

Relevant Experience:
 

• Strong expertise in protein chemistry and biochemical/biophysical characterization. 

• Experience in standard cellular and molecular biology techniques (Cell culture, ELISA, Cell-based assays, Immunofluorescence, Western blotting, Microscopy, RNA/DNA isolation, qPCR). 

• Experience with high-throughput screening. 

• Proven track record of success in leading research projects and contributing to scientific publications. 

• Excellent problem-solving skills, with the ability to troubleshoot complex biochemical/biological problems. 

• Strong communication skills, both written and verbal, with the ability to work effectively in a team-oriented environment. 

• Familiarity with regulatory requirements and documentation practices in a biotech or pharmaceutical setting. 

• Able to work as part of a team and individually. 
 

Why Join Akttyva Therapeutics? At Akttyva Therapeutics, you'll be part of a dynamic and collaborative culture that values innovation and impact. Join us in our quest to develop novel solutions for challenging diseases and make a tangible difference in the lives of patients around the world. 
 

How to Apply: If you are passionate about drug discovery projects, we would love to hear from you. Please submit your resume, cover letter, and a portfolio of relevant projects to Katya@akttyva.com