Research Tech/Staff Associate

Research Tech/Staff Associate

Human Immune Monitoring Core, Columbia University 

The Human Immune Monitoring Core (HIMC) at Columbia University Irving Medical Center offers cutting-edge single-cell services, including multi-modal single-cell genomics and transcriptomics, spatial transcriptomics, and other translational research assays for a diverse scientific and clinical research community.

We are seeking a motivated and talented Research Associate to support experimental workflows in molecular biology and preclinical models. The Candidate will work closely with scientists and clinicians to help design, implement and see-through cutting-edge research projects for discovery and translational research. The successful candidate will advise, train, and assist users in designing and executing single-cell genomics and spatial transcriptomics projects, while also contributing to other molecular biology, cloning, cell culture, and animal studies. The position provides opportunities for career development through collaborative studies, grant applications, and potential authorship on publications.

Responsibilities

• Engage with scientists and clinicians to design complex studies using patient samples or preclinical models.
• Perform molecular biology tasks, including cloning, PCR, and related workflows.
• Conduct mouse husbandry and assist with in vivo experimental procedures.
• Plan, oversee, and execute single-cell and spatial genomics assays.
• Test, benchmark, and implement novel methodologies.
• Develop, maintain, and ensure adherence to SOPs and quality standards.
• Assist with administrative laboratory operations, including purchasing, scheduling, and billing.
• Train and support technical staff as needed.
• Lead or participate in collaborative projects, apply for funding opportunities, and contribute to publications (if desired).

Qualifications

• Bachelor’s degree or higher in biological sciences, engineering, or related field.
• Strong experimental and analytical skills in molecular biology, particularly cloning and PCR.
• Experience with mouse handling and husbandry; prior in vivo research experience preferred.
• Familiarity with single-cell genomic assays and/or spatial transcriptomics (preferred).
• Strong organizational, interpersonal, and communication skills.
• Exceptional attention to detail.
• Ability to work independently and in collaboration with scientific leadership.
• Experience overseeing technical staff and/or training team members is a plus.

Commitment

Must be able to commit for a minimum of two years.