Research Associate
RiboForge is a stealth Venture-Backed biotechnology startup exploring the leading edge of RNA-targeted drug discovery. We are pioneering an innovative platform for developing potent small-molecule therapeutics against highly challenging disease-related RNA. We aim to achieve breakthroughs in RNA-targeted medicines for the treatment of cancer, neurodegenerative disease, and genetic disorders. Our team brings together experienced structural biologists, medicinal chemists, and entrepreneurs to accelerate the discovery of effective therapies in this exciting frontier.
We are seeking a highly skilled and motivated Research Associate who will take the lead in driving RNA production, structural characterization, and screening. The successful candidate will become part of a dynamic, rapidly growing team at UCLA’s beautiful Westwood campus. This is an excellent opportunity to advance your laboratory skills in a fast-paced organization that is working at the forefront of RNA biology. As an early hire, you will be a foundational member of the team and play a key role in launching compound discovery campaigns for multiple diseases.
Responsibilities
- Production of RNA by solid-phase synthesis or in vitro transcription
- RNA purification by gel electrophoresis or HPLC
- Sample characterization and quality control using LCMS
- Crystal screening, optimization, and diffraction studies
- High-throughput screening and hit validation
Minimum Qualifications
- Bachelor’s degree and a proven track record in laboratory research
- At least 2 years of prior lab experience in biochemistry or a related area
- Attention to detail and exceptional organizational skills
- A love of the scientific process and troubleshooting complex problems
Experience in the following would be a plus
- Experience working with RNA and nuclease-free technique
- Nucleic acid synthesis
- Structural biology, especially X-ray crystallography