Clinical Laboratory Technologist

Title:

Clinical Laboratory Technologist

Company Overview:

About SignatureDx:

In collaboration with the University of Pittsburgh and Magee-Womens Research Institute and Foundation, Signature is focused on the research and development of diagnostic and phenotyping tools for early-stage complex disease. In addition to its research facilities at Magee-Womens Research Institute, Signature operates SDxLabs, a CLIA certified high complexity molecular diagnostic laboratory that is both CAP and COLA Accredited.

Our Mission:

Signature is changing the paradigm of disease detection through new advanced technologies and novel diagnostic tools. Using a framework of noninvasive liquid biopsy to understand states of cellular function, Signature is focused on early detection of silently progressing complex disease. Signature is also dedicated to supporting women’s reproductive health by utilizing genetic tests to determine risks of pregnancy-related complications before they occur.

Our Approach:

Our approach utilizes novel lab techniques to process liquid biopsy samples that are then analyzed using pioneering algorithms and machine learning. This noninvasive screening method can serve as an early indication system by informing current disease state, and the likelihood of future disease development. This could reduce the expense, discomfort, and risks of traditional diagnostics. Using early detection as a means of proactive healthcare has the potential to drastically reduce the progression of organ disease and pregnancy-related complications.

Job Description:

As a Clinical Laboratory Technologist you will assist in the day-to-day clinical laboratory operations. The Clinical Laboratory Technologist will be responsible for independently and accurately performing high complexity molecular diagnostic tests. This role will perform all molecular lab procedures from start to finish according to standard operating procedures, analyzing results, and troubleshooting technical problems pertaining to specimen adequacy, laboratory data, and instrumentation.

Essential Duties and Responsibilities:

• Follow all documented Standard Operating Procedures (SOPs) for clinical laboratory processes, ensuring proper specimen handling, accurate recordkeeping, and compliance with quality standards.
• Evaluate and accession incoming specimens, organize workflow, and prioritize testing to ensure optimal efficiency and turnaround time.
• Accurately track patient specimens through the testing process using the Laboratory Information System (LIS).
• Prepare reagents and solutions in accordance with established protocols, maintaining proper documentation.
• Perform clinical testing and data analysis following SOPs, generating accurate and timely patient results.
• Conduct quality control, validation, and verification procedures to ensure clinical assay performance meets regulatory requirements.
• Maintain, calibrate, and troubleshoot laboratory instruments and equipment; promptly address technical issues to minimize downtime.
• Operate specialized laboratory instruments, molecular testing platforms, and associated software systems.
• Assist in the research and development of new molecular assays, including validation, performance studies, and SOP creation.
• Maintain a clean, safe, and organized work area in compliance with laboratory safety guidelines and PPE requirements.
• Monitor supply levels, manage inventory, and coordinate ordering to avoid workflow interruptions.
• Assist with training of new laboratory personnel and support ongoing skill development for current staff.
• Support preparation for inspections and audits from accrediting agencies, ensuring readiness and compliance.
• Participate in continuing education and complete all required training on time.
• Uphold strict patient confidentiality and HIPAA compliance at all times.
• Perform additional laboratory duties as assigned to support operational needs.

Requirements:

• Bachelors’ Degree in medical technology, clinical laboratory, chemical, physical or biological science.
• Minimum of 3 years lab experience performing molecular laboratory procedures in a high complexity testing environment. Molecular experience to include the performance of high complexity molecular techniques including DNA/RNA extraction, Real-Time PCR, Reverse-Transcriptase PCR, and data analysis and interpretation.
• Experience designing and conducting wet lab processes and genetic testing workflows.
• Experience working in a CAP/COLA accredited lab preferred.
• Must possess excellent pipetting skills (single and multi-channel) and thorough understanding of aseptic technique.
• Ability to organize workflow and lead other team members.
• Strong interpersonal skills with the ability to interact with individuals from a variety of levels and functions.
• Eagerness to learn and grow.
• Ability to work independently.
• Pleasant and positive attitude.
• Excellent written and verbal communication skills.
• Familiarity with Next Generation Sequencing techniques preferred.
• Familiarity with ThermoFisher QuantStudio (5, 12K flex or similar), KingFisher, Illumina sequencers preferred.
• Experience using Microsoft Office Suite of applications. Proficient in Microsoft Excel.
• Must pass background check.

Pay:

• $20-$28 Per Hour

Benefits

• PTO
• Dental
• Healthcare
• 401k Match
• Paid Holidays
• Identity Theft Insurance
• Disability Life insurance
• Professional Development

Travel

• <25%

EEOC Statement:

SignatureDx is an Equal opportunity Employer which means it will comply with all laws prohibiting discrimination against employees and applicants based on race, color, religion, sex, sexual orientation, gender identity, gender expression, age, national origin, citizenship status, disability, genetic information, or veterans' status.